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Understanding Septal Myectomy

Septal myectomy is a type of open-heart surgery. It’s done to treat hypertrophic cardiomyopathy. This is when part of the heart muscle becomes thick. The septum of the heart can become thickened because of family history of the disease or from uncontrolled high blood pressure. Diabetes and thyroid conditions may also be causes. The surgery helps ease symptoms of the condition.

Four-chamber view of heart with thickened septum and left ventricle. Shaded area shows part of septum to be removed in septal myectomy.

What is hypertrophic cardiomyopathy?

The heart has four chambers. The two lower chambers are called ventricles. The left and right ventricles are separated by a wall of muscle called the septum. With hypertrophic cardiomyopathy, the walls of the septum and the ventricles may get thick. The septum may bulge into the left ventricle. This can partly block the blood flow out to the body. This causes the heart to work harder. It also causes symptoms such as tiredness, chest pains, dizziness, and feeling short of breath with regular activity. In extreme cases, the decreased blood flow from the heart chamber to the body can cause you to faint or to develop dangerous and life-threatening heart rhythms.

Why septal myectomy is done

In many cases, medicine can relieve the symptoms. But if medicine doesn’t work well to relieve symptoms, a septal myectomy often works. A woman with hypertrophic cardiomyopathy may need the surgery before becoming pregnant. This may be the case even if her symptoms aren’t severe.

How septal myectomy is done

During septal myectomy, a surgeon removes extra muscle from the thickened septum. This lets the blood empty from the ventricle more easily.

Risks of septal myectomy

All procedures have risks. The risks of septal myectomy include:

  • Irregular heart rhythms, such as heart block (see below)

  • Infection

  • Bleeding

  • Blood clots that can lead to stroke or heart attack

  • Problems from anesthesia

  • Aortic valve problems because of movement of the valve in surgery

  • Removal of too much heart muscle

  • Blood flow problems during surgery that can lead to poor pumping of the heart in the future

Your own risks may vary based on your age and your overall health. Ask your healthcare provider which risks apply most to you. You may have a higher risk of problems if you have any of the below:

  • Chronic illness

  • Other heart conditions

  • Lung problems

  • Advanced age

  • Obesity

  • History of smoking

  • Infections

  • Diabetes

Heart block after septal myectomy

Heart block is a common problem after this surgery. Heart block is a disruption to the electrical signals through the heart. This can cause your heart to skip beats. Or it may beat too slowly. Some kinds of heart block need treatment with a pacemaker.

Online Medical Reviewer: Mary Mancini MD
Online Medical Reviewer: Raymond Turley Jr PA-C
Online Medical Reviewer: Stacey Wojcik MBA BSN RN
Date Last Reviewed: 12/1/2022
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